CrossRoads Missions Mexico intends to transform the city of Piedras Negras, Mexico, with the love and compassion of Christ through working alongside and empowering already-existing ministries by providing encouragement, home ownership opportunities, Christian education, medical clinics and youth programming.

Piedras Negras is at the northern border of the state of Coahuila in Mexico. It sits across the Rio Grande from Eagle Pass, Texas, and is about 150 miles southwest of San Antonio. The city's population is around 250,000 and continues to grow. Due to its border location, the city is significantly influenced by the U.S. in areas such as religion, media, and even language.